Coumarin Azide
3-Azido-7-Hydroxycoumarin | ||
Formula: C9H5N3O3 | M.W.: 203.15 |
Diluent: Not Applicable |
Refrigerated storage, maximum of 2-8°C, dry |
Stability in Solution: |
Glen Research is collaborating with baseclick Gmbh to offer a variety ofinteresting alkyne phosphoramidites. We offer some azide products and are nowembarking on an expansion of our azide catalog. Our strategy is to offer firstour most popular labels for general interest and, subsequently, we will addazide products that are not compatible with phosphoramidite chemistry.
Biotin is still our most commonly used label and biotinTEG, with itshydrophilic triethylene glycol spacer, is the most popular biotin product.Desthiobiotin is a biotin analogue that is well captured by streptavidin but thecaptured product can be easily released by applying a biotin solution to thestreptavidin beads. 6-FAM is our most popular fluorescein derivative and weoffer azides of both 6-FAM and pivaloyl-protected 6-FAM for situations wheresubsequent reactions require the 6-FAM to be protected. In both 6-FAM products,the hydrophilic TEG spacer is again used. The azides are offered in 25 and 100µmole packs for convenient oligonucleotide labelling.
7-Hydroxycoumarin, also known as umbelliferone, is a highly fluorescent,pH-sensitive fluorophore that emits in the blue region of the spectrum. However,its fluorescence is strongly quenched if the hydroxyl is alkylated orphosphorylated, making it useful in high-throughput screening for phosphatasesand lipases. Interestingly, it was found that the 3-azido derivative is alsohighly quenched but, upon reaction with an alkyne in the presence of copper toform the triazole, the fluorescence is restored.1 The clicked coumarin emits ata lambda max of 480 nm and absorbs at 358 nm.
HEX and TET are two of our most popular fluorescein-based dyes for labellingoligonucleotides. We are happy to offer 6-HEX and 6-TET Azides for use in clickconjugations.
If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200
Cambio成立于1985年,是一家私人控股的英国公司,在为大学、大型制药、生物技术、政府机构、农业组织和环境设施的科研实验室提供优质分子生物学试剂和耗材方面享有盛誉。
我们的产品来源于全球领先制造商网络,我们对我们长期的客户和供应商关系感到非常自豪,这促使Cambio致力于:
不断推出新产品
有竞争力的定价
无应力顺序排列
世界一流的技术支持
为了满足日益增长和多样化的市场需求,我们不断增加先进的分子生物学产品到我们广泛的产品组合中。我们目前的产品范围包括以下研究工具:
适体
农业食品诊断
细胞毒性和致突变性检测试剂盒
微阵列
寡合成
细胞培养污染控制
DNA和RNA测序
分子生物学用酶
染色体画
样品制备
分子克隆
转体
体外翻译
基因表达分析
塑料消耗品
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有趣的事实:
1986年,我们的创始董事彼得·迪恩(Peter Dean)与马丁·埃文斯(Martin Evans,现为教授)合作,开发了第一台使用专利“智能加热块(IHB)”技术进行PCR反应的机器,用于实时温度控制